• Anti-CD10 antibody [56C6] (STJ16101693)

Anti-CD10 antibody [56C6] (STJ16101693)

SKU:
STJ16101693-1

£1,514.50
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD10 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 56C6
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tissue culture supernatant with sodium azide
Dilution Range: IHC-P 1:100
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic recombinant fusion protein corresponding to the external domain of the human CD10 glycoprotein.
Background CD10 antigen, also called neprilysin, is a 100 kD cell surface metalloendopeptidase which inactivates a variety of biologically active peptides. It was initially identified as the common acute lymphoblastic leukemia antigen (CALLA) and was thought to be tumor-specific. Subsequent studies, however, have shown that CD10 antigen is expressed on the surface of a wide variety of normal and neoplastic cells. In other lymphoid malignancies, CD10 antigen is reported to be expressed on cells of lymphoblastic, Burkitt s and follicular lymphomas. CD10 antigen has been identified on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. It is also expressed in various non-lymphoid cells and tissues, such as breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. (G. McIntosh et al. American Journal of Pathology. 154 (1) : 77-82 (1999) ).

Information sourced from Uniprot.org

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