| Short Description : | Rabbit monoclonal anti-CCT2 for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-F/IHC-P/ICC/IF/IP |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R07-6C2 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.3 mg/mL |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:20 |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CCT2 |
| Gene ID: | 10576 |
| Uniprot ID: | TCPB_HUMAN |
| Immunogen: | A synthetic peptide of human CCT2 |
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit BetaTcp-1-BetaCct-BetaChaperonin Containing T-Complex Polypeptide 1 Subunit 2 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6798695Reactome: R-HSA-6814122Reactome: R-HSA-9013418Reactome: R-HSA-9013422 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Beta antibodyAnti-Tcp-1-Beta antibodyAnti-Cct-Beta antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 2 antibodyAnti-CCT2 antibodyAnti-99D8.1 antibodyAnti-CCTB antibody |
Information sourced from Uniprot.org
