Anti-CCNL1 antibody (461-510 aa) (STJ92548)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Cyclin L1 at the amino acid range 461-510
General Information
| Short Description | Rabbit polyclonal anti-Cyclin-L1 (461-510 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCNL1 |
| Gene ID | 57018 |
| Uniprot ID | CCNL1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Cyclin L1 at the amino acid range 461-510 |
| Immunogen Region | 461-510 aa |
| Specificity | Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein. |
Additional Info
| Function | Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). |
| Protein Name | Cyclin-L1Cyclin-L |
| Database Links | |
| Cellular Localisation | Nucleus SpeckleNucleusNucleoplasmFound In Nuclear Intrachromatin Granules Clusters (Igc)Also Called Nuclear SpecklesWhich Are Storage Compartments For Nuclear Proteins Involved In Mrna Processing |
| Alternative Antibody Names | Anti-Cyclin-L1 antibodyAnti-Cyclin-L antibodyAnti-CCNL1 antibodyAnti-BM-001 antibodyAnti-UNQ530 antibodyAnti-PRO1073 antibody |
Information sourced from Uniprot.org