| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cyclin-L1 (461-510 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCNL1 |
| Gene ID: | 57018 |
| Uniprot ID: | CCNL1_HUMAN |
| Immunogen Region: | 461-510 aa |
| Specificity: | Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Cyclin L1 at the amino acid range 461-510 |
| Function | Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). |
| Protein Name | Cyclin-L1Cyclin-L |
| Cellular Localisation | Nucleus SpeckleNucleusNucleoplasmFound In Nuclear Intrachromatin Granules Clusters (Igc)Also Called Nuclear SpecklesWhich Are Storage Compartments For Nuclear Proteins Involved In Mrna Processing |
| Alternative Antibody Names | Anti-Cyclin-L1 antibodyAnti-Cyclin-L antibodyAnti-CCNL1 antibodyAnti-BM-001 antibodyAnti-UNQ530 antibodyAnti-PRO1073 antibody |
Information sourced from Uniprot.org
