• Western blot analysis of lysates from HepG2 cells, using Cyclin L1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Cyclin L1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Cyclin L1 Polyclonal Antibody diluted at 1：1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-CCNL1 antibody (461-510 aa) (STJ92548)

SKU:
STJ92548

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cyclin-L1 (461-510 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCNL1
Gene ID: 57018
Uniprot ID: CCNL1_HUMAN
Immunogen Region: 461-510 aa
Specificity: Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Cyclin L1 at the amino acid range 461-510
Function Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC).
Protein Name Cyclin-L1
Cyclin-L
Cellular Localisation Nucleus Speckle
Nucleus
Nucleoplasm
Found In Nuclear Intrachromatin Granules Clusters (Igc)
Also Called Nuclear Speckles
Which Are Storage Compartments For Nuclear Proteins Involved In Mrna Processing
Alternative Antibody Names Anti-Cyclin-L1 antibody
Anti-Cyclin-L antibody
Anti-CCNL1 antibody
Anti-BM-001 antibody
Anti-UNQ530 antibody
Anti-PRO1073 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance