| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCNG1 |
| Gene ID: | 900 |
| Uniprot ID: | CCNG1_HUMAN |
| Immunogen Region: | 200-295 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-295 of human Cyclin G1 (NP_004051.1). |
| Immunogen Sequence: | PSVLALSIIALEIQAQKCVE LTEGIECLQKHSKINGRDLT FWQELVSKCLTEYSSNKCSK PNVQKLKWIVSGRTARQLKH SYYRITHLPTIPEMVP |
| Tissue Specificity | High levels in skeletal muscle, ovary, kidney and colon. |
| Function | May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. |
| Protein Name | Cyclin-G1 Cyclin-G |
| Database Links | Reactome: R-HSA-6804757 |
| Cellular Localisation | Nucleus Dna Replication Foci After Dna Damage |
| Alternative Antibody Names | Anti-Cyclin-G1 antibody Anti-Cyclin-G antibody Anti-CCNG1 antibody Anti-CCNG antibody Anti-CYCG1 antibody |
Information sourced from Uniprot.org