Function | Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. |
Protein Name | Ccn Family Member 4Wnt1-Inducible-Signaling Pathway Protein 1Wisp-1Wnt-1-Induced Secreted Protein |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Ccn Family Member 4 antibodyAnti-Wnt1-Inducible-Signaling Pathway Protein 1 antibodyAnti-Wisp-1 antibodyAnti-Wnt-1-Induced Secreted Protein antibodyAnti-CCN4 antibodyAnti-WISP1 antibody |
Information sourced from Uniprot.org