| Short Description : | Rabbit polyclonal CCL5 (29-52) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Ccl5Uniprot ID=CCL5_RAT" |
| Immunogen Region: | 29-52 |
| Immunogen Sequence: | SDTTPCCFAYLSLALPRAHV KEYF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-52 of rat CCL5 (AAA96499.1). |
| Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. |
| Protein Name | C-C Motif Chemokine 5Sis-DeltaSmall-Inducible Cytokine A5T-Cell-Specific Protein Rantes |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 5 antibodyAnti-Sis-Delta antibodyAnti-Small-Inducible Cytokine A5 antibodyAnti-T-Cell-Specific Protein Rantes antibodyAnti-Ccl5 antibodyAnti-Scya5 antibody |
Information sourced from Uniprot.org
