| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CCL3 and CCL3L1 (C-Term) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave bands at approx 26+28kDa (doublet) and 40kDa in Human Bone Marrow and Spleen lysates after 0.1µg/ml antibody staining.The 26+28kDa doublet was also found i |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CCL3 |
| Gene ID: | 6348 |
| Uniprot ID: | CCL3_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_002974.1; NP_066286.1 |
| Specificity: | Please note this product is expected to recognize the products of 2 different genes which are almost identical. |
| Immunogen Sequence: | EWVQKYVSDLELSA |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 3 antibodyAnti-G0/G1 Switch Regulatory Protein 19-1 antibodyAnti-Macrophage Inflammatory Protein 1-Alpha antibodyAnti-Mip-1-Alpha antibodyAnti-Pat 464.1 antibodyAnti-Sis-Beta antibodyAnti-Small-Inducible Cytokine A3 antibodyAnti-Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 antibodyAnti-Ld78-Alpha(4-69 antibodyAnti-CCL3 antibodyAnti-G0S19-1 antibodyAnti-MIP1A antibodyAnti-SCYA3 antibody |
Information sourced from Uniprot.org