Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CCL23 antibody (40-120 aa) (STJ191424)

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STJ191424
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-C-C motif chemokine 23 (40-120 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL23
Gene ID: 6368
Uniprot ID: CCL23_HUMAN
Immunogen Region: 40-120 aa
Specificity: CCL23 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 40-120
Post Translational Modifications The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23.
Protein Name C-C Motif Chemokine 23
Ck-Beta-8
Ckb-8
Macrophage Inflammatory Protein 3
Mip-3
Myeloid Progenitor Inhibitory Factor 1
Mpif-1
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99
Database Links Reactome: R-HSA-416476 P55773-2
Reactome: R-HSA-418594 P55773-2
Reactome: R-HSA-444473 P55773-2
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 23 antibody
Anti-Ck-Beta-8 antibody
Anti-Ckb-8 antibody
Anti-Macrophage Inflammatory Protein 3 antibody
Anti-Mip-3 antibody
Anti-Myeloid Progenitor Inhibitory Factor 1 antibody
Anti-Mpif-1 antibody
Anti-Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 antibody
Anti-CCL23 antibody
Anti-MIP3 antibody
Anti-MPIF1 antibody
Anti-SCYA23 antibody

Information sourced from Uniprot.org

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