| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Protein Name | C-C Motif Chemokine 19Beta-Chemokine Exodus-3Ck Beta-11Epstein-Barr Virus-Induced Molecule 1 Ligand ChemokineEbi1 Ligand ChemokineElcMacrophage Inflammatory Protein 3 BetaMip-3-BetaSmall-Inducible Cytokine A19 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 19 antibodyAnti-Beta-Chemokine Exodus-3 antibodyAnti-Ck Beta-11 antibodyAnti-Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine antibodyAnti-Ebi1 Ligand Chemokine antibodyAnti-Elc antibodyAnti-Macrophage Inflammatory Protein 3 Beta antibodyAnti-Mip-3-Beta antibodyAnti-Small-Inducible Cytokine A19 antibodyAnti-CCL19 antibodyAnti-ELC antibodyAnti-MIP3B antibodyAnti-SCYA19 antibody |
Information sourced from Uniprot.org
