Anti-CCL13 antibody (20-100 aa) (STJ191422)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 20-100
General Information
| Short Description | Rabbit polyclonal anti-C-C motif chemokine 13 (20-100 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL13 |
| Gene ID | 6357 |
| Uniprot ID | CCL13_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 20-100 |
| Immunogen Region | 20-100 aa |
| Specificity | CCL13 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| Protein Name | C-C Motif Chemokine 13Ck-Beta-10Monocyte Chemoattractant Protein 4Monocyte Chemotactic Protein 4Mcp-4Ncc-1Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 13 antibodyAnti-Ck-Beta-10 antibodyAnti-Monocyte Chemoattractant Protein 4 antibodyAnti-Monocyte Chemotactic Protein 4 antibodyAnti-Mcp-4 antibodyAnti-Ncc-1 antibodyAnti-Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain antibodyAnti-CCL13 antibodyAnti-MCP4 antibodyAnti-NCC1 antibodyAnti-SCYA13 antibody |
Information sourced from Uniprot.org