Immunohistochemistry analysis of CCK antibody in paraffin-embedded human brain tissue.

Anti-CCK antibody (46-95 aa) (STJ92071)

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STJ92071
€60.00 - €315.00
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Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Cholecystokinin (46-95 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCK
Gene ID: 885
Uniprot ID: CCKN_HUMAN
Immunogen Region: 46-95 aa
Specificity: CCK Polyclonal Antibody detects endogenous levels of CCK protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CCK at the amino acid range 46-95
Post Translational Modifications The precursor is cleaved by proteases to produce a number of active cholecystokinins. Cholecystokinin-5: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Name Cholecystokinin
Cck Cleaved Into - Cholecystokinin-58
Cck58 - Cholecystokinin-58 Desnonopeptide
(1-49-Cck58 - Cholecystokinin-39
Cck39 - Cholecystokinin-33
Cck33 - Cholecystokinin-25
Cck25 - Cholecystokinin-18
Cck18 - Cholecystokinin-12
Cck12 - Cholecystokinin-8
Cck8 - Cholecystokinin-7
Cck7 - Cholecystokinin-5
Cck5
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Cholecystokinin antibody
Anti-Cck Cleaved Into - Cholecystokinin-58 antibody
Anti-Cck58 - Cholecystokinin-58 Desnonopeptide antibody
Anti-(1-49-Cck58 - Cholecystokinin-39 antibody
Anti-Cck39 - Cholecystokinin-33 antibody
Anti-Cck33 - Cholecystokinin-25 antibody
Anti-Cck25 - Cholecystokinin-18 antibody
Anti-Cck18 - Cholecystokinin-12 antibody
Anti-Cck12 - Cholecystokinin-8 antibody
Anti-Cck8 - Cholecystokinin-7 antibody
Anti-Cck7 - Cholecystokinin-5 antibody
Anti-Cck5 antibody
Anti-CCK antibody

Information sourced from Uniprot.org

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