| Post Translational Modifications | The precursor is cleaved by proteases to produce a number of active cholecystokinins. Cholecystokinin-5: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone. |
| Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
| Protein Name | CholecystokininCck Cleaved Into - Cholecystokinin-58Cck58 - Cholecystokinin-58 Desnonopeptide(1-49-Cck58 - Cholecystokinin-39Cck39 - Cholecystokinin-33Cck33 - Cholecystokinin-25Cck25 - Cholecystokinin-18Cck18 - Cholecystokinin-12Cck12 - Cholecystokinin-8Cck8 - Cholecystokinin-7Cck7 - Cholecystokinin-5Cck5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cholecystokinin antibodyAnti-Cck Cleaved Into - Cholecystokinin-58 antibodyAnti-Cck58 - Cholecystokinin-58 Desnonopeptide antibodyAnti-(1-49-Cck58 - Cholecystokinin-39 antibodyAnti-Cck39 - Cholecystokinin-33 antibodyAnti-Cck33 - Cholecystokinin-25 antibodyAnti-Cck25 - Cholecystokinin-18 antibodyAnti-Cck18 - Cholecystokinin-12 antibodyAnti-Cck12 - Cholecystokinin-8 antibodyAnti-Cck8 - Cholecystokinin-7 antibodyAnti-Cck7 - Cholecystokinin-5 antibodyAnti-Cck5 antibodyAnti-CCK antibody |
Information sourced from Uniprot.org
