Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Mitochondrial potassium channel (357-407 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCDC51 |
Gene ID: | 79714 |
Uniprot ID: | MITOK_HUMAN |
Immunogen Region: | 357-407 aa |
Specificity: | This antibody detects endogenous levels of CCD51 at Human/Mouse/Rat |
Immunogen: | Synthesized peptide derived from the human CCD51 at the amino acid range 357-407 |
Function | Pore-forming subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)). Together with ATP-binding subunit ABCB8/MITOSUR of the mitoK(ATP) channel, mediates ATP-dependent K(+) currents across the mitochondrial inner membrane. An increase in ATP intracellular levels closes the channel, inhibiting K(+) transport, whereas a decrease in ATP levels enhances K(+) uptake in the mitochondrial matrix. May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. |
Protein Name | Mitochondrial Potassium ChannelMitokCoiled-Coil Domain-Containing Protein 51 |
Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinIsoform 1: Mitochondrion Inner Membrane |
Alternative Antibody Names | Anti-Mitochondrial Potassium Channel antibodyAnti-Mitok antibodyAnti-Coiled-Coil Domain-Containing Protein 51 antibodyAnti-CCDC51 antibodyAnti-MITOK antibody |
Information sourced from Uniprot.org