| Function | Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly. Recruits NIN and CEP170 to centrosomes. Also required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth. |
| Protein Name | Coiled-Coil Domain-Containing Protein 120 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCell ProjectionNeuron ProjectionGrowth ConeEndosomeLocalizes To The Subdistal Appendages Of Mother Centrioles And Proximal Ends Of Both Centrioles In Interphase CellsRecruited To Subdistal Appendages By Odf2In Differentiating Neuroblastoma CellsColocalizes With Cyth2 In Both Neurite Shaft And Growth Cone AreasPartially Colocalizes With Endosomes Along Neurites In Differentiating Neuroblastoma Cells |
| Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Protein 120 antibodyAnti-CCDC120 antibodyAnti-JM11 antibody |
Information sourced from Uniprot.org
