| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-CBX1/HP1-Beta (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1.0 µg/mlIHC-Recommended concentration, 2-3µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
CBX1 |
| Gene ID: |
10951 |
| Uniprot ID: |
CBX1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_006798.1; NP_001120700.1 |
| Specificity: |
Variants (NP_006798.1; NP_001120700.1) encode the same protein. |
| Immunogen Sequence: |
QSQKTAHETDKSE |
| Post Translational Modifications | Not phosphorylated. Ubiquitinated. |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Protein Name | Chromobox Protein Homolog 1Hp1hsbetaHeterochromatin Protein 1 Homolog BetaHp1 BetaHeterochromatin Protein P25M31Modifier 1 ProteinP25beta |
| Database Links | Reactome: R-HSA-9609690 |
| Cellular Localisation | NucleusUnassociated With Chromosomes During Mitosis |
| Alternative Antibody Names | Anti-Chromobox Protein Homolog 1 antibodyAnti-Hp1hsbeta antibodyAnti-Heterochromatin Protein 1 Homolog Beta antibodyAnti-Hp1 Beta antibodyAnti-Heterochromatin Protein P25 antibodyAnti-M31 antibodyAnti-Modifier 1 Protein antibodyAnti-P25beta antibodyAnti-CBX1 antibodyAnti-CBX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
