• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CBR3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from Jurkat and MCF7 cells, using CBR3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Carbonyl Reductase 3 Polyclonal Antibody

Anti-CBR3 antibody (151-200 aa) (STJ91998)

SKU:
STJ91998

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Carbonyl reductase 3 (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CBR3
Gene ID: 874
Uniprot ID: CBR3_HUMAN
Immunogen Region: 151-200 aa
Specificity: Carbonyl Reductase 3 Polyclonal Antibody detects endogenous levels of Carbonyl Reductase 3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CBR3 at the amino acid range 151-200
Function Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified.
Protein Name Carbonyl Reductase Nadph 3
Nadph-Dependent Carbonyl Reductase 3
Quinone Reductase Cbr3
Short Chain Dehydrogenase/Reductase Family 21c Member 2
Database Links Reactome: R-HSA-211945
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Carbonyl Reductase Nadph 3 antibody
Anti-Nadph-Dependent Carbonyl Reductase 3 antibody
Anti-Quinone Reductase Cbr3 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 21c Member 2 antibody
Anti-CBR3 antibody
Anti-SDR21C2 antibody

Information sourced from Uniprot.org

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