Anti-CAVIN2 antibody (129-179 aa) (STJ194248)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SDPR at the amino acid range 129-179
General Information
| Short Description | Rabbit polyclonal anti-Caveolae-associated protein 2 (129-179 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAVIN2 |
| Gene ID | 8436 |
| Uniprot ID | CAVN2_HUMAN |
| Immunogen | Synthesized peptide derived from the human SDPR at the amino acid range 129-179 |
| Immunogen Region | 129-179 aa |
| Specificity | This antibody detects endogenous levels of SDPR at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Phosphorylated on Ser residues. |
| Function | Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae. |
| Protein Name | Caveolae-Associated Protein 2Cavin-2Ps-P68Phosphatidylserine-Binding ProteinSerum Deprivation-Response Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolMembraneCaveolaLocalizes In The Caveolae In A Caveolin-Dependent Manner |
| Alternative Antibody Names | Anti-Caveolae-Associated Protein 2 antibodyAnti-Cavin-2 antibodyAnti-Ps-P68 antibodyAnti-Phosphatidylserine-Binding Protein antibodyAnti-Serum Deprivation-Response Protein antibodyAnti-CAVIN2 antibodyAnti-SDPR antibody |
Information sourced from Uniprot.org