• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CAVIN2 antibody (129-179 aa) (STJ194248)

SKU:
STJ194248

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Caveolae-associated protein 2 (129-179 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAVIN2
Gene ID: 8436
Uniprot ID: CAVN2_HUMAN
Immunogen Region: 129-179 aa
Specificity: This antibody detects endogenous levels of SDPR at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human SDPR at the amino acid range 129-179
Post Translational Modifications Phosphorylated on Ser residues.
Function Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae.
Protein Name Caveolae-Associated Protein 2
Cavin-2
Ps-P68
Phosphatidylserine-Binding Protein
Serum Deprivation-Response Protein
Cellular Localisation Cytoplasm
Cytosol
Membrane
Caveola
Localizes In The Caveolae In A Caveolin-Dependent Manner
Alternative Antibody Names Anti-Caveolae-Associated Protein 2 antibody
Anti-Cavin-2 antibody
Anti-Ps-P68 antibody
Anti-Phosphatidylserine-Binding Protein antibody
Anti-Serum Deprivation-Response Protein antibody
Anti-CAVIN2 antibody
Anti-SDPR antibody

Information sourced from Uniprot.org

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