| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CATSPER1 |
| Gene ID: | 117144 |
| Uniprot ID: | CTSR1_HUMAN |
| Immunogen Region: | 1-210 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CATSPER1 (NP_444282.3). |
| Immunogen Sequence: | MDQNSVPEKAQNEADTNNAD RFFRSHSSPPHHRPGHSRAL HHYELHHHGVPHQRGESHHP PEFQDFHDQALSSHVHQSHH HSEARNHGRAHGPTGFGLAP SQGAVPSHRSYGEDYHDELQ RDGRRHHDGSQYGGFHQQSD SHYHRGSHHGRPQYLGENLS HYSSGVPHHGEASHHGGSYL PHGPNPYSESFHHSEASHLS GLQHDESQHH |
| Tissue Specificity | Testis-specific. |
| Function | Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. |
| Protein Name | Cation Channel Sperm-Associated Protein 1Catsper1Hcatsper |
| Database Links | Reactome: R-HSA-1300642 |
| Cellular Localisation | Cell ProjectionCiliumFlagellum MembraneMulti-Pass Membrane ProteinSpecifically Located In The Principal Piece Of The Sperm Tail |
| Alternative Antibody Names | Anti-Cation Channel Sperm-Associated Protein 1 antibodyAnti-Catsper1 antibodyAnti-Hcatsper antibodyAnti-CATSPER1 antibody |
Information sourced from Uniprot.org
