| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IF |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Cathepsin K (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
CTSK |
| Gene ID: |
1513 |
| Uniprot ID: |
CATK_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_000387.1 |
| Immunogen Sequence: |
KTHRKQYNNKVDE |
| Function | Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. |
| Protein Name | Cathepsin KCathepsin OCathepsin O2Cathepsin X |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-1679131Reactome: R-HSA-2132295Reactome: R-HSA-8939242 |
| Cellular Localisation | LysosomeSecretedApical Cell MembranePeripheral Membrane ProteinExtracellular SideLocalizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells |
| Alternative Antibody Names | Anti-Cathepsin K antibodyAnti-Cathepsin O antibodyAnti-Cathepsin O2 antibodyAnti-Cathepsin X antibodyAnti-CTSK antibodyAnti-CTSO antibodyAnti-CTSO2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
