| Tissue Specificity | Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines. |
| Post Translational Modifications | Phosphorylated on tyrosines by SRC. |
| Function | Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. |
| Protein Name | Cas Scaffolding Protein Family Member 4Hef-Like ProteinHef1-Efs-P130cas-Like ProteinHepl |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal Adhesion |
| Alternative Antibody Names | Anti-Cas Scaffolding Protein Family Member 4 antibodyAnti-Hef-Like Protein antibodyAnti-Hef1-Efs-P130cas-Like Protein antibodyAnti-Hepl antibodyAnti-CASS4 antibodyAnti-C20orf32 antibodyAnti-HEFL antibody |
Information sourced from Uniprot.org
