• Immunohistochemistry analysis of Casein Kinase 2 beta (CSNK2B) in paraffin-embedded mouse testis using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) Rabbit polyclonal antibody (STJ11102908) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of Casein Kinase 2 beta (CSNK2B) in paraffin-embedded human thyroid cancer using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) Rabbit polyclonal antibody (STJ11102908) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of Casein Kinase 2 beta (CSNK2B) in paraffin-embedded rat lung using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) Rabbit polyclonal antibody (STJ11102908) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) Rabbit polyclonal antibody (STJ11102908) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-Casein Kinase 2 beta antibody (1-215) (STJ11102908)

SKU:
STJ11102908

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Casein Kinase 2 beta (CSNK2B) (1-215) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CSNK2B
Gene ID: 1460
Uniprot ID: CSK2B_HUMAN
Immunogen Region: 1-215
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) (NP_001311.3).
Immunogen Sequence: MSSSEEVSWISWFCGLRGNE FFCEVDEDYIQDKFNLTGLN EQVPHYRQALDMILDLEPDE ELEDNPNQSDLIEQAAEMLY GLIHARYILTNRGIAQMLEK YQQGDFGYCPRVYCENQPML PIGLSDIPGEAMVKLYCPKC MDVYTPKSSRHHHTDGAYFG TGFPHMLFMVHPEYRPKRPA NQFVPRLYGFKIHPMAYQLQ LQAASNFKSPVKTIR
Post Translational Modifications Phosphorylated by alpha subunit.
Function Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling. (Microbial infection) Upon infection with Epstein-Barr virus (EBV), the interaction with viral EBNA1 increases the association of CK2 with PML proteins, which increases PML phosphorylation by CK2, triggering the polyubiquitylation and degradation of PML. Seems to also suppress EBV reactivation by mediating ARK2N and JUN at the Z promoter which inhibits BZLF1 transcrition.
Protein Name Casein Kinase Ii Subunit Beta
Ck Ii Beta
Phosvitin
Protein G5a
Database Links Reactome: R-HSA-1483191
Reactome: R-HSA-201688
Reactome: R-HSA-2514853
Reactome: R-HSA-445144
Reactome: R-HSA-6798695
Reactome: R-HSA-6804756
Reactome: R-HSA-6814122
Reactome: R-HSA-8934903
Reactome: R-HSA-8939243
Reactome: R-HSA-8948751
Reactome: R-HSA-9755511
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Casein Kinase Ii Subunit Beta antibody
Anti-Ck Ii Beta antibody
Anti-Phosvitin antibody
Anti-Protein G5a antibody
Anti-CSNK2B antibody
Anti-CK2N antibody
Anti-G5A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance