| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Caspase recruitment domain-containing protein 19 (21-70 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD19 |
| Gene ID: | 84270 |
| Uniprot ID: | CAR19_HUMAN |
| Immunogen Region: | 21-70 aa |
| Specificity: | BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human C9orf89 at the amino acid range 21-70 |
| Function | Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 19Bcl10-Interacting Card ProteinBincard |
| Cellular Localisation | Isoform 1: NucleusCoexpression With Bcl10 Induced Translocation From Nucleus To CytosolIsoform 2: Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Membrane |
| Alternative Antibody Names | Anti-Caspase Recruitment Domain-Containing Protein 19 antibodyAnti-Bcl10-Interacting Card Protein antibodyAnti-Bincard antibodyAnti-CARD19 antibodyAnti-C9orf89 antibody |
Information sourced from Uniprot.org