| Short Description : | Rabbit polyclonal anti-Caspase recruitment domain-containing protein 18 (30-110 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD18 |
| Gene ID: | 59082 |
| Uniprot ID: | CAR18_HUMAN |
| Immunogen: | Synthesized peptide derived from the human CAR18 at the amino acid range 30-110 |
| Immunogen Region: | 30-110 aa |
| Specificity: | This antibody detects endogenous levels of CAR18 at Human |
| Function | Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 18Caspase-1 Inhibitor Iceberg |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Caspase Recruitment Domain-Containing Protein 18 antibodyAnti-Caspase-1 Inhibitor Iceberg antibodyAnti-CARD18 antibodyAnti-ICEBERG antibodyAnti-UNQ5804 antibodyAnti-PRO19611 antibody |
Information sourced from Uniprot.org
