Anti-CARD17 antibody (STJA0004496)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human CARD17
General Information
| Short Description | Rabbit polyclonal anti-Putative Caspase Recruitment Domain-Containing Protein 17p for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.7 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CARD17PUniprot ID=CAR17_HUMAN" |
| Immunogen | Synthetic peptide of human CARD17 |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Putative Caspase Recruitment Domain-Containing Protein 17p antibodyAnti-Caspase-1 Inhibitor Inca antibodyAnti-Inhibitory Caspase Recruitment Domain Protein antibodyAnti-CARD17P antibodyAnti-CARD17 antibodyAnti-INCA antibody |
Information sourced from Uniprot.org