Anti-CAPN3 antibody (STJ190642)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Calpain-3 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPN3 |
| Gene ID | 825 |
| Uniprot ID | CAN3_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | CAN3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53. |
| Protein Name | Calpain-3Calcium-Activated Neutral Proteinase 3Canp 3Calpain L3Calpain P94Muscle-Specific Calcium-Activated Neutral Protease 3New Calpain 1Ncl-1 |
| Database Links | Reactome: R-HSA-1474228 |
| Cellular Localisation | CytoplasmNucleusNucleolus |
| Alternative Antibody Names | Anti-Calpain-3 antibodyAnti-Calcium-Activated Neutral Proteinase 3 antibodyAnti-Canp 3 antibodyAnti-Calpain L3 antibodyAnti-Calpain P94 antibodyAnti-Muscle-Specific Calcium-Activated Neutral Protease 3 antibodyAnti-New Calpain 1 antibodyAnti-Ncl-1 antibodyAnti-CAPN3 antibodyAnti-CANP3 antibodyAnti-CANPL3 antibodyAnti-NCL1 antibody |
Information sourced from Uniprot.org