| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Macrophage-capping protein is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CAPG |
| Gene ID: | 822 |
| Uniprot ID: | CAPG_HUMAN |
| Specificity: | This antibody detects endogenous levels of CAPG at Human, Rat |
| Immunogen: | Synthesized peptide derived from human CAPG |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
| Protein Name | Macrophage-Capping ProteinActin Regulatory Protein Cap-G |
| Cellular Localisation | NucleusCytoplasmMelanosomeCell ProjectionLamellipodiumRuffleIn MacrophagesMay Be Predominantly CytoplasmicNuclear Localization Was Observed In FibroblastsPresent At The Membrane-Cytoplasm InterfaceIn Activated MacrophagesConcentrated In The Ruffles Of The Leading Lamellipodia |
| Alternative Antibody Names | Anti-Macrophage-Capping Protein antibodyAnti-Actin Regulatory Protein Cap-G antibodyAnti-CAPG antibodyAnti-AFCP antibodyAnti-MCP antibody |
Information sourced from Uniprot.org