| Short Description : | Goat polyclonal antibody anti-CAPE (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 140kDa band observed in lysates of cell line HeLa (calculated MW of 136kDa according to NP_006435.2). Recommended concentration: 0.2-0.6µg/ml. |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SMC2 |
| Gene ID: | 10592 |
| Uniprot ID: | SMC2_HUMAN |
| Accession Number: | NP_006435.2 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | SKAKPPKGAHVEV |
| Specificity: | Reported variants NP_006435.2, NP_001036015.1 and NP_001036016.1 represent identical protein |
| Protein Name | Structural Maintenance Of Chromosomes Protein 2Smc Protein 2Smc-2Chromosome-Associated Protein EHcap-EXcap-E Homolog |
| Database Links | Reactome: R-HSA-2299718Reactome: R-HSA-2514853 |
| Cellular Localisation | NucleusCytoplasmChromosomeIn Interphase CellsThe Majority Of The Condensin Complex Is Found In The CytoplasmWhile A Minority Of The Complex Is Associated With ChromatinA Subpopulation Of The Complex However Remains Associated With Chromosome Foci In Interphase CellsDuring MitosisMost Of The Condensin Complex Is Associated With The ChromatinAt The Onset Of ProphaseThe Regulatory Subunits Of The Complex Are Phosphorylated By Cdc2Leading To Condensin's Association With Chromosome Arms And To Chromosome CondensationDissociation From Chromosomes Is Observed In Late Telophase |
| Alternative Antibody Names | Anti-Structural Maintenance Of Chromosomes Protein 2 antibodyAnti-Smc Protein 2 antibodyAnti-Smc-2 antibodyAnti-Chromosome-Associated Protein E antibodyAnti-Hcap-E antibodyAnti-Xcap-E Homolog antibodyAnti-SMC2 antibodyAnti-CAPE antibodyAnti-SMC2L1 antibodyAnti-PRO0324 antibody |
Information sourced from Uniprot.org
