| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CANT1 |
| Gene ID: | 124583 |
| Uniprot ID: | CANT1_HUMAN |
| Immunogen Region: | 62-231 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-231 of human CANT1 (NP_620148.1). |
| Immunogen Sequence: | HRPAPGRPPTHNAHNWRLGQ APANWYNDTYPLSPPQRTPA GIRYRIAVIADLDTESRAQE ENTWFSYLKKGYLTLSDSGD KVAVEWDKDHGVLESHLAEK GRGMELSDLIVFNGKLYSVD DRTGVVYQIEGSKAVPWVIL SDGDGTVEKGFKAEWLAVKD ERLYVGGLGK |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis. |
| Protein Name | Soluble Calcium-Activated Nucleotidase 1Scan-1Apyrase HomologPutative Mapk-Activating Protein Pm09Putative Nf-Kappa-B-Activating Protein 107 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi ApparatusGolgi Stack MembraneCell MembraneProcessed Form: Secreted |
| Alternative Antibody Names | Anti-Soluble Calcium-Activated Nucleotidase 1 antibodyAnti-Scan-1 antibodyAnti-Apyrase Homolog antibodyAnti-Putative Mapk-Activating Protein Pm09 antibodyAnti-Putative Nf-Kappa-B-Activating Protein 107 antibodyAnti-CANT1 antibodyAnti-SHAPY antibody |
Information sourced from Uniprot.org