| Tissue Specificity | Expressed in granulocytes (at protein level). High expression in bone marrow and small intestine. Expressed in testis, spleen, stomach, and intestine. Very low expression found in heart, lung and skeletal muscle. No expression in brain, kidney or liver. |
| Post Translational Modifications | Proteolytically cleaved by cathepsin CTSG. |
| Function | Antimicrobial protein that is an integral component of the innate immune system. Binds to bacterial lipopolysaccharides (LPS). Cathelin-related antimicrobial peptide: Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2. |
| Protein Name | Cathelicidin Antimicrobial PeptideCathelin-Like ProteinClp Cleaved Into - Cathelin-Related Antimicrobial PeptideCramp |
| Database Links | Reactome: R-MMU-6798695Reactome: -MMU-6803157 |
| Cellular Localisation | SecretedVesicleStored As Pro-Peptide In Granules And Phagolysosomes Of Neutrophils |
| Alternative Antibody Names | Anti-Cathelicidin Antimicrobial Peptide antibodyAnti-Cathelin-Like Protein antibodyAnti-Clp Cleaved Into - Cathelin-Related Antimicrobial Peptide antibodyAnti-Cramp antibodyAnti-Camp antibodyAnti-Cnlp antibodyAnti-Cramp antibody |
Information sourced from Uniprot.org
