Anti-Calumenin antibody [R05-1E7] (STJA0035139)

SKU:
STJA0035139
$184.23 - $388.47
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Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Calumenin for use in WB and IHC-P in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R05-1E7
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: CALU
Gene ID: 813
Uniprot ID: CALU_HUMAN
Immunogen: A synthetic peptide of human Calumenin
Tissue Specificity Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
Function Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
Protein Name Calumenin
Crocalbin
Ief Ssp 9302
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Endoplasmic Reticulum Membrane
Golgi Apparatus
Secreted
Melanosome
Sarcoplasmic Reticulum Lumen
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Calumenin antibody
Anti-Crocalbin antibody
Anti-Ief Ssp 9302 antibody
Anti-CALU antibody

Information sourced from Uniprot.org