| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CALU (20-315) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CALU |
| Gene ID: |
813 |
| Uniprot ID: |
CALU_HUMAN |
| Immunogen Region: |
20-315 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-315 of human CALU (NP_001210.1). |
| Immunogen Sequence: |
KPTEKKDRVHHEPQLSDKVH NDAQSFDYDHDAFLGAEEAK TFDQLTPEESKERLGKIVSK IDGDKDGFVTVDELKDWIKF AQKRWIYEDVERQWKGHDLN EDGLVSWEEYKNATYGYVLD DPDPDDGFNYKQMMVRDERR FKMADKDGDLIATKEEFTAF LHPEEYDYMKDIVVQETMED IDKNADGFIDLEEYIGDMYS HDGNTDEPEWVKTEREQFVE FRDKNRDGKMDKEETKDWI |
| Tissue Specificity | Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver. |
| Function | Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. |
| Protein Name | CalumeninCrocalbinIef Ssp 9302 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Endoplasmic Reticulum MembraneGolgi ApparatusSecretedMelanosomeSarcoplasmic Reticulum LumenIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Calumenin antibodyAnti-Crocalbin antibodyAnti-Ief Ssp 9302 antibodyAnti-CALU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
