Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-calreticulin (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human and Rat Lung lysates (calculated MW of 48.1kDa according to NP_004334.1). These bands correspond to earlier findings in literature with different a |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
CALR |
Gene ID: |
811 |
Uniprot ID: |
CALR_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_004334.1 |
Immunogen Sequence: |
HPEIDNPEYSPDPS |
Protein Name | CalreticulinCrp55CalregulinEndoplasmic Reticulum Resident Protein 60Erp60HacbpGrp60 |
Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-168316Reactome: R-HSA-3000480Reactome: R-HSA-3000484Reactome: R-HSA-381183Reactome: R-HSA-901042Reactome: R-HSA-983170 |
Cellular Localisation | Endoplasmic Reticulum LumenCytoplasmCytosolSecretedExtracellular SpaceExtracellular MatrixCell SurfaceSarcoplasmic Reticulum LumenCytoplasmic VesicleSecretory VesicleCortical GranuleCytolytic GranuleAlso Found In Cell Surface (T Cells)Cytosol And Extracellular MatrixDuring Oocyte Maturation And After Parthenogenetic Activation Accumulates In Cortical GranulesIn Pronuclear And Early Cleaved Embryos Localizes Weakly To Cytoplasm Around Nucleus And More Strongly In The Region Near The CortexIn Cortical Granules Of Non-Activated OocytesIs Exocytosed During The Cortical Reaction In Response To Oocyte Activation |
Alternative Antibody Names | Anti-Calreticulin antibodyAnti-Crp55 antibodyAnti-Calregulin antibodyAnti-Endoplasmic Reticulum Resident Protein 60 antibodyAnti-Erp60 antibodyAnti-Hacbp antibodyAnti-Grp60 antibodyAnti-CALR antibodyAnti-CRTC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance