Anti-Calponin 2/CNN2 antibody (Internal) (STJ71998)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Calponin 2/CNN2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 35kDa band observed in lysates of cell line HepG2 (calculated MW of 33.7kDa according to NP_004359.1). Recommended concentration: 0.03-0.1ยตg/ml. Primary incubation was 1 hour. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CNN2 |
| Gene ID | 1265 |
| Uniprot ID | CNN2_HUMAN |
| Accession Number | NP_004359.1; NP_958434.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DPGEVPEYPPYYQEE |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_004359.1; NP_958434.1) , but it is not expected to cross-react with CCN3. |
Additional Info
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Protein Name | Calponin-2Calponin H2 - Smooth MuscleNeutral Calponin |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8950505 |
| Alternative Antibody Names | Anti-Calponin-2 antibodyAnti-Calponin H2 - Smooth Muscle antibodyAnti-Neutral Calponin antibodyAnti-CNN2 antibody |
Information sourced from Uniprot.org