• Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CALHM3 antibody (191-241 aa) (STJ195195)

SKU:
STJ195195

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calcium homeostasis modulator protein 3 (191-241 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CALHM3
Gene ID: 119395
Uniprot ID: CAHM3_HUMAN
Immunogen Region: 191-241 aa
Specificity: This antibody detects endogenous levels of CAHM3 at Human
Immunogen: Synthesized peptide derived from the human CAHM3 at the amino acid range 191-241
Function Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Protein Name Calcium Homeostasis Modulator Protein 3
Protein A
Database Links Reactome: R-HSA-9717207
Reactome: R-HSA-9730628
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Calcium Homeostasis Modulator Protein 3 antibody
Anti-Protein A antibody
Anti-CALHM3 antibody
Anti-FAM26A antibody

Information sourced from Uniprot.org

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