| Host: | Goat |
| Applications: | Pep-ELISA/WB/IF/FC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Calcipressin-1 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx. 40kDa band was observed in Human Cerebellum lysates (calculated MW of 31.9kDa according to NP_001272320.2). This molecular weight is observed by other commercial sources, and w |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RCAN1 |
| Gene ID: | 1827 |
| Uniprot ID: | RCAN1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_004405.3; NP_981962.1; NP_981963.1 |
| Specificity: | This antibody is expected to recognize all three reported isoforms (NP_004405.3; NP_981962.1; NP_981963.1). |
| Immunogen Sequence: | HIGSSHLAPPNPD |
| Post Translational Modifications | Phosphorylation increases its ability to inhibit calcineurin and decreases protein half-life. |
| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. |
| Protein Name | Calcipressin-1Adapt78Down Syndrome Critical Region Protein 1Myocyte-Enriched Calcineurin-Interacting Protein 1Mcip1Regulator Of Calcineurin 1 |
| Alternative Antibody Names | Anti-Calcipressin-1 antibodyAnti-Adapt78 antibodyAnti-Down Syndrome Critical Region Protein 1 antibodyAnti-Myocyte-Enriched Calcineurin-Interacting Protein 1 antibodyAnti-Mcip1 antibodyAnti-Regulator Of Calcineurin 1 antibodyAnti-RCAN1 antibodyAnti-ADAPT78 antibodyAnti-CSP1 antibodyAnti-DSC1 antibodyAnti-DSCR1 antibody |
Information sourced from Uniprot.org