Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Calcitonin gene-related peptide 1 (71-120 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CALCA |
Gene ID: |
796 |
Uniprot ID: |
CALCA_HUMAN |
Immunogen Region: |
71-120 aa |
Specificity: |
CALCA Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 71-120 |
Function | CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex. |
Protein Name | Calcitonin Gene-Related Peptide 1Cgrp1Alpha-Type CgrpCalcitonin Gene-Related Peptide ICgrp-I |
Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812Reactome: R-HSA-977225 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Calcitonin Gene-Related Peptide 1 antibodyAnti-Cgrp1 antibodyAnti-Alpha-Type Cgrp antibodyAnti-Calcitonin Gene-Related Peptide I antibodyAnti-Cgrp-I antibodyAnti-CALCA antibodyAnti-CALC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance