Anti-CACNG8 antibody (Internal Region) (STJ13100844)

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STJ13100844-100
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Short Description :Rabbit polyclonal anti-CACNG8 (Internal Region) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:CACNG8
Gene ID:59283
Uniprot ID:CCG8_HUMAN
Immunogen:A synthetic peptide from the internal region of human CACNG8 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
Immunogen Region:Internal Region
Specificity:Specific for CACNG8.
Post Translational Modifications Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7.
Function Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.
Protein Name Voltage-Dependent Calcium Channel Gamma-8 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-8 Subunit
Transmembrane Ampar Regulatory Protein Gamma-8
Tarp Gamma-8
Database Links Reactome: R-HSA-399719
Reactome: R-HSA-5576892
Reactome: R-HSA-5576893
Reactome: R-HSA-5682910
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Postsynaptic Density Membrane
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-8 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-8 Subunit antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-8 antibody
Anti-Tarp Gamma-8 antibody
Anti-CACNG8 antibody
Anti-CACNG6 antibody

Information sourced from Uniprot.org

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