Western blot analysis of extracts of various cell lines, using CACNG7 antibody (STJ110296) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CACNG7 antibody (156-275) (STJ110296)

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STJ110296
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNG7
Gene ID: 59284
Uniprot ID: CCG7_HUMAN
Immunogen Region: 156-275
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 156-275 of human CACNG7 (NP_114102.2).
Immunogen Sequence: INDEVMNRPSSSEQYFHYRY GWSFAFAASSFLLKEGAGVM SVYLFTKRYAEEEMYRPHPA FYRPRLSDCSDYSGQFLQPE AWRRGRSPSDISSDVSIQMT QNYPPAIKYPDHLHISTSPC
Tissue Specificity Detected in heart left ventricle. Widely expressed.
Function Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2.
Protein Name Voltage-Dependent Calcium Channel Gamma-7 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-7 Subunit
Transmembrane Ampar Regulatory Protein Gamma-7
Tarp Gamma-7
Database Links Reactome: R-HSA-5576892
Reactome: R-HSA-5576893
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-7 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-7 Subunit antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-7 antibody
Anti-Tarp Gamma-7 antibody
Anti-CACNG7 antibody

Information sourced from Uniprot.org

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