| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Voltage-dependent calcium channel gamma-4 subunit (120-200 aa) for use in WB, IHC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:1000-2000IHC 1:200-500IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CACNG4 |
| Gene ID: | 27092 |
| Uniprot ID: | CCG4_HUMAN |
| Immunogen Region: | 120-200 aa |
| Specificity: | The antibody detects endogenous L-type Ca++ CP Gamma 4 protein. |
| Immunogen: | Synthetic peptide derived from L-type Ca++ CP Gamma 4 at the amino acid range 120-200 |
| Function | Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-4 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-4 SubunitTransmembrane Ampar Regulatory Protein Gamma-4Tarp Gamma-4 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-399719Reactome: R-HSA-5576892Reactome: R-HSA-5576893Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-4 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-4 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-4 antibodyAnti-Tarp Gamma-4 antibodyAnti-CACNG4 antibody |
Information sourced from Uniprot.org
