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Anti-CACNB2 antibody (500-600) (STJ500387)

Western blot with Anti-CACNB2 Antibody (STJ500387) on ear cells (A) and peptide at 1:500 dilution in buffer.

Anti-CACNB2 antibody (500-600) (STJ500387)

SKU:

STJ500387-100

£441.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CACNB2 (500-600) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.6 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Cacnb2
Gene ID:	116600
Uniprot ID:	CACB2_RAT
Immunogen Region:	500-600
Immunogen:	Synthetic peptide taken within amino acid region 500-600 on rat voltage-dependent L-type calcium channel subunit beta-2 protein

Tissue Specificity	Highly expressed in heart and brain, and at lower levels in lung.
Post Translational Modifications	Regulated through phosphorylation at Thr-549 by CaMK2D.
Function	Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.
Protein Name	Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 Cab2 Calcium Channel Voltage-Dependent Subunit Beta 2
Database Links	Reactome: R-RNO-112308 Reactome: -RNO-422356 Reactome: -RNO-5576892 Reactome: -RNO-5576893
Cellular Localisation	Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side
Alternative Antibody Names	Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 antibody Anti-Cab2 antibody Anti-Calcium Channel Voltage-Dependent Subunit Beta 2 antibody Anti-Cacnb2 antibody Anti-Cacnlb2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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