Anti-CACNB2 antibody (500-600) {Biotin} (STJ500388)

SKU:
STJ500388-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNB2 (500-600) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.6 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cacnb2
Gene ID: 116600
Uniprot ID: CACB2_RAT
Immunogen Region: 500-600
Immunogen: Synthetic peptide taken within amino acid region 500-600 on rat voltage-dependent L-type calcium channel subunit beta-2 protein
Tissue Specificity Highly expressed in heart and brain, and at lower levels in lung.
Post Translational Modifications Regulated through phosphorylation at Thr-549 by CaMK2D.
Function Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.
Protein Name Voltage-Dependent L-Type Calcium Channel Subunit Beta-2
Cab2
Calcium Channel Voltage-Dependent Subunit Beta 2
Database Links Reactome: R-RNO-112308
Reactome: -RNO-422356
Reactome: -RNO-5576892
Reactome: -RNO-5576893
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 antibody
Anti-Cab2 antibody
Anti-Calcium Channel Voltage-Dependent Subunit Beta 2 antibody
Anti-Cacnb2 antibody
Anti-Cacnlb2 antibody

Information sourced from Uniprot.org

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