| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CA5A |
| Gene ID: | 763 |
| Uniprot ID: | CAH5A_HUMAN |
| Immunogen Region: | 39-305 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-305 of human CA5A (NP_001730.1). |
| Immunogen Sequence: | CAWQTSNNTLHPLWTVPVSV PGGTRQSPINIQWRDSVYDP QLKPLRVSYEAASCLYIWNT GYLFQVEFDDATEASGISGG PLENHYRLKQFHFHWGAVNE GGSEHTVDGHAYPAELHLVH WNSVKYQNYKEAVVGENGLA VIGVFLKLGAHHQTLQRLVD ILPEIKHKDARAAMRPFDPS TLLPTCWDYWTYAGSLTTPP LTESVTWIIQKEPVEVAPSQ LSAFRTLLFSALGEEEKMM |
| Function | Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles. |
| Protein Name | Carbonic Anhydrase 5a - MitochondrialCarbonate Dehydratase VaCarbonic Anhydrase VaCa-Va |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 5a - Mitochondrial antibodyAnti-Carbonate Dehydratase Va antibodyAnti-Carbonic Anhydrase Va antibodyAnti-Ca-Va antibodyAnti-CA5A antibodyAnti-CA5 antibody |
Information sourced from Uniprot.org