| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CA15-3 is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 4404 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1, IgG/k |
| Formulation: | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: | Purity accurate to greater than or equal to 95% |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | 12 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 days OK +35 °C, 7 days OK +35 °C, 21 days Failed due to reduced antigen binding +45 °C, 3 days OK +45 °C, 7 days OK, some cha |
| Determination Method: | Radioimmunoassay (RIA) |
| Immunoreactivity: | 80–120 % compared to the reference sample in an FIA test |
| Immunogen: | MUC-1 core protein of cancer antigen 15-3 |
| Background | Cancer Antigen 15-3 is defined by the use of two monoclonal antibodies, one specific for MUC-1 protein core and another antibody specific for a sialylated carbohydrate epitope on the MUC-1 protein. CA15-3 is a widely used serum marker in breast cancer patients for monitoring their response to cancer therapy. |
Information sourced from Uniprot.org