| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C5AR2 |
| Gene ID: | 27202 |
| Uniprot ID: | C5AR2_HUMAN |
| Immunogen Region: | 258-337 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-337 of human C5AR2 (NP_060955.1). |
| Immunogen Sequence: | VAAPNSALLARALRAEPLIV GLALAHSCLNPMLFLYFGRA QLRRSLPAACHWALRESQGQ DESVDSKKSTSHDLVSEMEV |
| Tissue Specificity | Frontal cortex, hippocampus, hypothalamus, pons and liver. |
| Function | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. |
| Protein Name | C5a Anaphylatoxin Chemotactic Receptor 2Complement Component 5a Receptor 2G-Protein Coupled Receptor 77 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 2 antibodyAnti-Complement Component 5a Receptor 2 antibodyAnti-G-Protein Coupled Receptor 77 antibodyAnti-C5AR2 antibodyAnti-C5L2 antibodyAnti-GPR77 antibody |
Information sourced from Uniprot.org
