Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | C5AR2 |
Gene ID: | 27202 |
Uniprot ID: | C5AR2_HUMAN |
Immunogen Region: | 258-337 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-337 of human C5AR2 (NP_060955.1). |
Immunogen Sequence: | VAAPNSALLARALRAEPLIV GLALAHSCLNPMLFLYFGRA QLRRSLPAACHWALRESQGQ DESVDSKKSTSHDLVSEMEV |
Tissue Specificity | Frontal cortex, hippocampus, hypothalamus, pons and liver. |
Function | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. |
Protein Name | C5a Anaphylatoxin Chemotactic Receptor 2Complement Component 5a Receptor 2G-Protein Coupled Receptor 77 |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-977606 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 2 antibodyAnti-Complement Component 5a Receptor 2 antibodyAnti-G-Protein Coupled Receptor 77 antibodyAnti-C5AR2 antibodyAnti-C5L2 antibodyAnti-GPR77 antibody |
Information sourced from Uniprot.org