• Western blot analysis of lysates from HeLa cells, treated with PMA 125ng/ml 30', using CD88/C5aR Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HeLa cells, using CD88/C5aR Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD88/C5aR Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CD88 Polyclonal Antibody

Anti-C5AR1 antibody (301-350 aa) (STJ92146)

SKU:
STJ92146

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C5a anaphylatoxin chemotactic receptor 1 (301-350 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C5AR1
Gene ID: 728
Uniprot ID: C5AR1_HUMAN
Immunogen Region: 301-350 aa
Specificity: CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human N ternal CD88/C5aR at the amino acid range 301-350
Function Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Protein Name C5a Anaphylatoxin Chemotactic Receptor 1
C5a Anaphylatoxin Chemotactic Receptor
C5a-R
C5ar
Cd Antigen Cd88
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Reactome: R-HSA-977606
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Phosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles
Alternative Antibody Names Anti-C5a Anaphylatoxin Chemotactic Receptor 1 antibody
Anti-C5a Anaphylatoxin Chemotactic Receptor antibody
Anti-C5a-R antibody
Anti-C5ar antibody
Anti-Cd Antigen Cd88 antibody
Anti-C5AR1 antibody
Anti-C5AR antibody
Anti-C5R1 antibody

Information sourced from Uniprot.org

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