| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C3AR1 (161-337) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C3AR1 |
| Gene ID: |
719 |
| Uniprot ID: |
C3AR_HUMAN |
| Immunogen Region: |
161-337 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 161-337 of human C3AR1 (NP_004045.1). |
| Immunogen Sequence: |
REIFTTDNHNRCGYKFGLSS SLDYPDFYGDPLENRSLENI VQPPGEMNDRLDPSSFQTND HPWTVPTVFQPQTFQRPSAD SLPRGSARLTSQNLYSNVFK PADVVSPKIPSGFPIEDHET SPLDNSDAFLSTHLKLFPSA SSNSFYESELPQGFQDYYNL GQFTDDDQVPTPLVAIT |
| Tissue Specificity | Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues. |
| Post Translational Modifications | Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated. |
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
| Protein Name | C3a Anaphylatoxin Chemotactic ReceptorC3arC3a-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-9660826Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C3a Anaphylatoxin Chemotactic Receptor antibodyAnti-C3ar antibodyAnti-C3a-R antibodyAnti-C3AR1 antibodyAnti-AZ3B antibodyAnti-C3R1 antibodyAnti-HNFAG09 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
