Anti-C2CD6 antibody (491-540 aa) (STJ91567)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ALS2CR11 at the amino acid range 491-540
General Information
| Short Description | Rabbit polyclonal anti-Cation channel sperm-associated targeting subunit tau (491-540 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | C2CD6 |
| Gene ID | 151254 |
| Uniprot ID | CTSRT_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ALS2CR11 at the amino acid range 491-540 |
| Immunogen Region | 491-540 aa |
| Specificity | ALS2CR11 Polyclonal Antibody detects endogenous levels of ALS2CR11 protein. |
Additional Info
| Function | Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins. |
| Protein Name | Cation Channel Sperm-Associated Targeting Subunit TauCatsper-TauAmyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 11 ProteinC2 Calcium-Dependent Domain-Containing Protein 6 |
| Database Links | |
| Cellular Localisation | Cell ProjectionCiliumFlagellum MembraneSpecifically Located In The Principal Piece Of Sperm Tail |
| Alternative Antibody Names | Anti-Cation Channel Sperm-Associated Targeting Subunit Tau antibodyAnti-Catsper-Tau antibodyAnti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 11 Protein antibodyAnti-C2 Calcium-Dependent Domain-Containing Protein 6 antibodyAnti-C2CD6 antibodyAnti-ALS2CR11 antibodyAnti-CATSPERT antibody |
Information sourced from Uniprot.org