| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adipolin (193-243 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C1QTNF12 |
| Gene ID: |
388581 |
| Uniprot ID: |
ADIPL_HUMAN |
| Immunogen Region: |
193-243 aa |
| Specificity: |
This antibody detects endogenous levels of F132A at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human F132A at the amino acid range 193-243 |
| Post Translational Modifications | Processed into Adipolin fC1QTNF12 and Adipolin gC1QTNF12 by FURIN. Insulin enhances endogenous C1QTNF12 cleavage. |
| Function | Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. |
| Protein Name | AdipolinAdipose-Derived Insulin-Sensitizing FactorC1q And Tnf Related Protein 12Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12Adipolin Fctrp12Adipolin Full-Length Form - Adipolin Gc1qtnf12Adipolin Cleaved FormAdipolin Gctrp12 |
| Cellular Localisation | Adipolin Fc1qtnf12: SecretedAdipolin Gc1qtnf12: SecretedIn Sera Is The Predominant Form |
| Alternative Antibody Names | Anti-Adipolin antibodyAnti-Adipose-Derived Insulin-Sensitizing Factor antibodyAnti-C1q And Tnf Related Protein 12 antibodyAnti-Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12 antibodyAnti-Adipolin Fctrp12 antibodyAnti-Adipolin Full-Length Form - Adipolin Gc1qtnf12 antibodyAnti-Adipolin Cleaved Form antibodyAnti-Adipolin Gctrp12 antibodyAnti-C1QTNF12 antibodyAnti-C1QDC2 antibodyAnti-CTRP12 antibodyAnti-FAM132A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
