| Host: | Rabbit |
| Applications: | WB/FC/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Complement C1q subcomponent subunit B (161-210 aa) is suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 FC 1:50-200 IHC-P 1:100-500 IF ICC 1:100-500 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C1QB |
| Gene ID: | 713 |
| Uniprot ID: | C1QB_HUMAN |
| Immunogen Region: | 161-210 aa |
| Specificity: | C1q-B Polyclonal Antibody detects endogenous levels of C1q-B protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human C1QB at the amino acid range 161-210 |
| Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Protein Name | Complement C1q Subcomponent Subunit B |
| Database Links | Reactome: R-HSA-166663 Reactome: R-HSA-173623 Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement C1q Subcomponent Subunit B antibody Anti-C1QB antibody |
Information sourced from Uniprot.org